South America

South America Cruises

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Recommended Sailings

SOUTH AMERICA CRUISES

  • MSC Poesia

    9 Night South America

    MSC Poesia

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Camboriu, Brazil
    • Ilhabela, Brazil
    • Buzios, Brazil
    • Rio De Janeiro, Brazil
    Sailing Dates:
    • January 2025
    • February 2025
    interior from
    $879
    $98pernight
    oceanview from
    $1,109
    $123pernight
    balcony from
    $1,309
    $145pernight
    suite from
    $2,289
    $254pernight
    All the Cruise Line Offers & More:
    • Memorial Day Sale: Limited-Time Reduced Rates
    • The MSC Cruise Experience: Click to Learn More
    • Escape to Sea Sale!
     
    Was $1,579 – Save up to 44%
    Interior from $879
    ($98pernight)
  • MSC Poesia

    9 Night South America

    MSC Poesia

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Porto Belo, Brazil
    • Ilhabela, Brazil
    • Buzios, Brazil
    • Rio De Janeiro, Brazil
    Sailing Dates:
    • March 2025
    interior from
    $909
    $101pernight
    oceanview from
    $1,139
    $127pernight
    balcony from
    $1,339
    $149pernight
    suite from
    $2,319
    $258pernight
    All the Cruise Line Offers & More:
    • Memorial Day Sale: Limited-Time Reduced Rates
    • The MSC Cruise Experience: Click to Learn More
    • Escape to Sea Sale!
     
    Was $1,639 – Save up to 45%
    Interior from $909
    ($101pernight)
  • Sapphire Princess

    18 Night Brazilian Adventure

    Sapphire Princess

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Basseterre, St. Kitts
    • Fortaleza, Brazil
    • Rio De Janeiro, Brazil
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Sailing Dates:
    • November 2024
    interior from
    $998
    $55pernight
    oceanview from
    $1,117
    $62pernight
    balcony from
    $1,648
    $92pernight
    suite from
    $2,298
    $128pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $100 to Spend on Board - Call
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • Get Up To $1,000 to Spend on Board
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Save Up to 35% off + 3rd & 4th Guests Sail Free!
     
    Interior from $998
    ($55pernight)
  • Sapphire Princess

    18 Night Andes & South America

    Sapphire Princess

    Departing from: San Antonio (Santiago), Chile
    Ports of Call:
    • Coquimbo (La Serena), Chile
    • General San Martin (Pisco), Peru
    • Callao (Lima), Peru
    • Manta, Ecuador
    • Puntarenas, Costa Rica
    • Puerto Vallarta, Mexico
    • Cabo San Lucas, Mexico
    • San Pedro (Los Angeles), California
    Sailing Dates:
    • March 2025
    interior from
    $1,148
    $64pernight
    oceanview from
    $1,272
    $71pernight
    balcony from
    $1,998
    $111pernight
    suite from
    $2,898
    $161pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $100 to Spend on Board - Call
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • Get Up To $1,000 to Spend on Board
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Save Up to 35% off + 3rd & 4th Guests Sail Free!
     
    Interior from $1,148
    ($64pernight)
  • Majestic Princess

    18 Night Brazilian Adventure

    Majestic Princess

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Santos (Sao Paulo), Brazil
    • Rio De Janeiro, Brazil
    • Fortaleza, Brazil
    • Dominica
    • Basseterre, St. Kitts
    • Ft. Lauderdale (Port Everglades), Florida
    Sailing Dates:
    • January 2025
    interior from
    $1,148
    $64pernight
    oceanview from
    Not Available
    balcony from
    $1,798
    $100pernight
    suite from
    $2,398
    $133pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $100 to Spend on Board - Call
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • Get Up To $1,000 to Spend on Board
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Save Up to 35% off + 3rd & 4th Guests Sail Free!
     
    Interior from $1,148
    ($64pernight)
  • Majestic Princess

    18 Night Andes & South America

    Majestic Princess

    Departing from: San Pedro (Los Angeles), California
    Ports of Call:
    • Puerto Vallarta, Mexico
    • Panama City (Fuerte Amador), Panama
    • Callao (Lima), Peru
    • Pisco (Nazca Lines), Peru
    • Coquimbo (La Serena), Chile
    • San Antonio (Santiago), Chile
    Sailing Dates:
    • December 2024
    interior from
    $1,178
    $65pernight
    oceanview from
    Not Available
    balcony from
    $1,236
    $69pernight
    suite from
    $2,198
    $122pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $100 to Spend on Board - Call
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • Get Up To $1,000 to Spend on Board
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Save Up to 35% off + 3rd & 4th Guests Sail Free!
     
    Interior from $1,178
    ($65pernight)
  • Norwegian Star

    16 Night Transatlantic: Brazil & Canary Islands

    Norwegian Star - OPEN BAR!

    Departing from: Rio De Janeiro, Brazil
    Ports of Call:
    • Buzios, Brazil
    • Salvador De Bahia, Brazil
    • Maceio, Brazil
    • Recife, Brazil
    • Porto Grande, Cape Verde Islands
    • Santa Maria, Azores, Portugal
    • Santa Cruz De Tenerife, Canary Islands
    • Las Palmas, Gran Canaria, Canary Islands
    • Funchal, Madeira, Portugal
    • Lisbon, Portugal
    Sailing Dates:
    • March 2025
    interior from
    $1,319
    $82pernight
    oceanview from
    $1,399
    $87pernight
    balcony from
    $2,439
    $152pernight
    suite from
    $2,629
    $164pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $400 to Spend on Board
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Second Guest Flies Free
    • Save up to $150 Instantly! Call and Mention: CruiseFirst
    • Get Up To $1,000 to Spend on Board
    • 35% Off All Cruises + Free at Sea Perks
     
    Interior from $1,319
    ($82pernight)
  • Sapphire Princess

    14 Night Cape Horn & Strait of Magellan

    Sapphire Princess

    Departing from: San Antonio (Santiago), Chile
    Ports of Call:
    • Puerto Montt, Chile
    • Cruise Amalia Glacier
    • Punta Arenas, Chile
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Cape Horn
    • Port Stanley, Falkland Islands
    • Puerto Madryn, Argentina
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Sailing Dates:
    • February 2025
    interior from
    $1,248
    $89pernight
    oceanview from
    $1,316
    $94pernight
    balcony from
    $2,848
    $203pernight
    suite from
    $3,248
    $232pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $100 to Spend on Board - Call
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • Get Up To $1,000 to Spend on Board
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Save Up to 35% off + 3rd & 4th Guests Sail Free!
     
    Interior from $1,248
    ($89pernight)
  • Oosterdam

    14 Night South America Passage

    Oosterdam

    Departing from: San Antonio (Santiago), Chile
    Ports of Call:
    • Puerto Montt, Chile
    • Puerto Chacabuco, Chile
    • Cruise Chilean Fjords
    • Scenic Cruising Sarmiento Channel
    • Cruise Strait Of Magellan
    • Punta Arenas, Chile
    • Cruise Cockburn & Beagle Channels
    • Cruise Glacier Alley
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Cape Horn
    • Port Stanley, Falkland Islands
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Sailing Dates:
    • December 2024
    • February 2025
    • December 2025
    • February 2026
    interior from
    $1,309
    $94pernight
    oceanview from
    $1,409
    $101pernight
    balcony from
    $2,459
    $176pernight
    suite from
    $3,159
    $226pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $150 to Spend on Board
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Get Up To $1,000 to Spend on Board
    • Free Drinks, Dining, and Excursions with Select Fares
    • Anniversary Sale: Save Up to 45% Off, Up to $300 to Spend on Board & More
     
    Interior from $1,309
    ($94pernight)
  • Celebrity Equinox

    14 Night Patagonia & Argentina

    Celebrity Equinox

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Port Stanley, Falkland Islands
    • Cruise Cape Horn
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Strait Of Magellan
    • Punta Arenas, Chile
    • Puerto Madryn, Argentina
    • Punta Del Este, Uruguay
    Sailing Dates:
    • December 2025
    • February 2026
    interior from
    $1,421
    $102pernight
    oceanview from
    $1,535
    $110pernight
    balcony from
    $1,908
    $136pernight
    suite from
    $5,983
    $427pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Get Up To $1,000 to Spend on Board
    • All-Included: Free Drinks & Wi-Fi
    • Flash Sale: 75% Off 2nd Guests & Up to $200 in Savings!
    • CALL: up to a $75 FREE Dining Credit!
     
    Interior from $1,421
    ($102pernight)
  • Sapphire Princess

    14 Night Cape Horn & Strait of Magellan

    Sapphire Princess

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Puerto Madryn, Argentina
    • Port Stanley, Falkland Islands
    • Cruise Cape Horn
    • Ushuaia, Tierra Del Fuego, Argentina
    • Punta Arenas, Chile
    • Cruise Amalia Glacier
    • Puerto Montt, Chile
    • San Antonio (Santiago), Chile
    Sailing Dates:
    • February 2025
    • March 2025
    interior from
    $1,298
    $93pernight
    oceanview from
    $1,369
    $98pernight
    balcony from
    $3,198
    $228pernight
    suite from
    $3,348
    $239pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $100 to Spend on Board - Call
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • Get Up To $1,000 to Spend on Board
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Save Up to 35% off + 3rd & 4th Guests Sail Free!
     
    Interior from $1,298
    ($93pernight)
  • Oosterdam

    14 Night South America Passage

    Oosterdam

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Port Stanley, Falkland Islands
    • Cruise Cape Horn
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Beagle Channel
    • Cruise Glacier Alley
    • Cruise Strait Of Magellan
    • Punta Arenas, Chile
    • Cruise Cockburn Channel
    • Cruise Strait Of Magellan
    • Puerto Montt, Chile
    • San Antonio (Santiago), Chile
    Sailing Dates:
    • March 2025
    • March 2026
    interior from
    $1,509
    $108pernight
    oceanview from
    $1,609
    $115pernight
    balcony from
    $2,459
    $176pernight
    suite from
    $3,359
    $240pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $150 to Spend on Board
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Get Up To $1,000 to Spend on Board
    • Free Drinks, Dining, and Excursions with Select Fares
    • Anniversary Sale: Save Up to 45% Off, Up to $300 to Spend on Board & More
     
    Interior from $1,509
    ($108pernight)
  • Norwegian Jade

    17 Night South America: Cabo & Trujillo

    Norwegian Jade - OPEN BAR!

    Departing from: Callao (Lima), Peru
    Ports of Call:
    • Salaverry (Trujillo), Peru
    • Manta, Ecuador
    • Panama City, Panama
    • Puntarenas, Costa Rica
    • San Juan Del Sur, Nicaragua
    • Acajutla, El Salvador
    • Puerto Quetzal, Guatemala
    • Huatulco, Mexico
    • Acapulco, Mexico
    • Manzanillo, Mexico
    • Puerto Vallarta, Mexico
    • Cabo San Lucas, Mexico
    • San Diego, California
    Sailing Dates:
    • March 2026
    interior from
    $1,739
    $102pernight
    oceanview from
    $2,249
    $132pernight
    balcony from
    $3,699
    $218pernight
    suite from
    $4,479
    $263pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $400 to Spend on Board
    • Second Guest Flies Free
    • Save up to $150 Instantly! Call and Mention: CruiseFirst
    • 35% Off All Cruises + Free at Sea Perks
     
    Interior from $1,739
    ($102pernight)
  • Celebrity Equinox

    14 Night Patagonia & Argentina Holiday

    Celebrity Equinox

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Port Stanley, Falkland Islands
    • Cruise Cape Horn
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Strait Of Magellan
    • Punta Arenas, Chile
    • Puerto Madryn, Argentina
    • Punta Del Este, Uruguay
    Sailing Dates:
    • December 2025
    interior from
    $1,786
    $128pernight
    oceanview from
    $2,135
    $153pernight
    balcony from
    $2,698
    $193pernight
    suite from
    $7,383
    $527pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Get Up To $1,000 to Spend on Board
    • All-Included: Free Drinks & Wi-Fi
    • Flash Sale: 75% Off 2nd Guests & Up to $200 in Savings!
    • CALL: up to a $75 FREE Dining Credit!
     
    Interior from $1,786
    ($128pernight)
  • Majestic Princess

    15 Night Cape Horn & Strait of Magellan

    Majestic Princess

    Departing from: San Antonio (Santiago), Chile
    Ports of Call:
    • Puerto Montt, Chile
    • Cruise Amalia Glacier
    • Punta Arenas, Chile
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Cape Horn
    • Port Stanley, Falkland Islands
    • Puerto Madryn, Argentina
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Sailing Dates:
    • December 2024
    interior from
    $2,128
    $142pernight
    oceanview from
    Not Available
    balcony from
    $2,896
    $193pernight
    suite from
    $3,698
    $247pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $100 to Spend on Board - Call
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • Get Up To $1,000 to Spend on Board
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Save Up to 35% off + 3rd & 4th Guests Sail Free!
     
    Interior from $2,128
    ($142pernight)
  • Azamara Journey

    10 Night Peru & Chile Voyage

    Azamara Journey

    Departing from: Callao (Lima), Peru
    Ports of Call:
    • Pisco (Nazca Lines), Peru
    • Arica, Chile
    • Iquique, Chile
    • Antofagasta, Chile
    • Coquimbo (La Serena), Chile
    • San Antonio (Santiago), Chile
    Sailing Dates:
    • January 2025
    interior from
    $2,900
    $290pernight
    oceanview from
    $3,401
    $340pernight
    balcony from
    $4,001
    $400pernight
    suite from
    $6,401
    $640pernight
    All the Cruise Line Offers & More:
    • Choose from up to $1,000 Spending or Air Savings
    • Luxury Transportation Credit - call to book!
    • Free Gratuities, Select Beverages, Exclusive Cultural Events, and More
     
    Interior from $2,900
    ($290pernight)
  • Viking Sea

    12 Night Amazon & Caribbean Adventure

    Viking Sea

    Departing from: Manaus (Amazon River), Brazil
    Ports of Call:
    • Parintins (Amazon River), Brazil
    • Santarem (Amazon River), Brazil
    • Cruise Amazon River
    • Devils Island, French Guiana
    • Bridgetown, Barbados
    • Castries, St. Lucia
    • Basseterre, St. Kitts
    • San Juan, Puerto Rico
    Sailing Dates:
    • December 2024
    • January 2025
    • March 2025
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $3,999
    $333pernight
    suite from
    $5,999
    $500pernight
    All the Cruise Line Offers & More:
    • Special Savings; Free or Reduced Airfare
    • Limited Time: $25 Deposits
    • Viking Exclusive: Up to $1,000 to Spend on Board
    • Includes Abundant Dining Options, Wi-Fi, more
    • Call for the Best Value
     
    Balcony from $3,999
    ($333pernight)
  • Viking Sea

    12 Night Amazon & Caribbean Adventure

    Viking Sea

    Departing from: San Juan, Puerto Rico
    Ports of Call:
    • St. Johns, Antigua
    • Castries, St. Lucia
    • Bridgetown, Barbados
    • Devils Island, French Guiana
    • Cruise Amazon River
    • Santarem (Amazon River), Brazil
    • Parintins (Amazon River), Brazil
    • Manaus (Amazon River), Brazil
    Sailing Dates:
    • November 2024
    • January 2025
    • February 2025
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $4,599
    $383pernight
    suite from
    $6,999
    $583pernight
    All the Cruise Line Offers & More:
    • Special Savings; Free or Reduced Airfare
    • Limited Time: $25 Deposits
    • Viking Exclusive: Up to $1,000 to Spend on Board
    • Includes Abundant Dining Options, Wi-Fi, more
    • Call for the Best Value
     
    Balcony from $4,599
    ($383pernight)

Experience the Thrill of a South America Cruise

Get the Best Deals on a South America Cruise

Take pleasure in a cruise adventure of a lifetime when you travel to South America with CruiseWise.

Your sailing will begin from the always chic and star-studded city of Miami, FL. Enjoy South Florida’s most famed district by soaking up the sun on South Beach, dine in a beachside restaurant or relax at an outdoor café.

Aboard a grand ship, you’ll set sail for places like Cartagena, a city known for its exterior beauty resting on the northern coast of Columbia in the Caribbean Coast Region. Colon, Panama is a popular cruise destination, and one you won’t want to miss. Its main attraction, arguably, is the infamous Panama Canal, one of the world’s greatest engineering feats made by man.

To the east, your South America cruise itineraries include ports like Santos (Sao Paulo), Brazil, where the soft sands of the beaches connect with the crystal blue waters of the Atlantic. In Buenos Aires, visit Plaza Intendente Alvear, an event livened area littered with street performers, colorful crafts and souvenir markets. Lose yourself in the street fairs of Montevideo, Uruguay and indulge in a local dish, or shop till you drop in one of many specialty boutiques.

A South America cruise with CruiseWise offers a wide-range of diverse pleasure-seeking activities such as shopping, exceptional sightseeing, beach fun, new dining experiences and more.

South America Cruises


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